… Further investigation revealed that bacteriorhodopsin … re-protonation via proton donor Asp-96
in the N560 intermediate. … 52-1 heliorhodopsin (TaHeR), studied in this thesis, is a member …

… the intermediates of rhodopsin's photocycle, using time-… ; therefore, it is hard to illustrate
every single residue's effect … to initiate new projects and work independently. He helped me to …

… and most significant residue identified in this study that sustained … annotation as
bacteriorhodopsin-like proteins was the pres… of key Asp and Thr residues, and a slower photocycle …

… T-89, and D-96 in bacteriorhodopsin are highlighted by orange … The common ancestor to
the sequences used in this study … In contrast, the Asn-Asp-Gln (NDQ) motif of Na+ pumping …

… the study of the prototypical proton pump, bacteriorhodopsin … Several (though not all) double
mutations which removed the … (B) Crystal structure of BR, showing Asp-85 and Asp-96, the …

… D85, T89, and D96 residues of the proton pump bacteriorhodopsin (BR 7 )) … We substituted
E64 with Leu and Gln and studied … Black arrow indicates different orientation of Asn residue of …

… , like the Asp in position 96 in bacteriorhodopsin” and serves … from Asp to Asn and proton
uptake position from typical Asp to Gln… leastsquares fitting program MEXFIT (93). The number of …

… and the structurally related bacteriorhodopsin are considered prototypes for the study of the
… of highly conserved residues and motifs within the large GPCR family. Thus, our studies will …

… The Asn residues in the motif carry partial charges which … in aquaglyceroporins, there is a
Leu-Leu pair which is less bulky … from the primary proton donor Asp 96 to be transferred to the …

… pairs, to identify conformational changes in bacteriorhodopsin [80… location of the fusion
peptide region of HIV gp41 [93]. … in lipid bilayers by similar measurements [96]. As shown by C–F …